CASE REPORT
Year : 2015  |  Volume : 8  |  Issue : 3  |  Page : 407-410

Recurrent metastatic mixed germ cell tumor of central nervous system with additional seminomatous component


1 Department of Pathology, Kasturba Medical College, Mangalore, Karnataka, India
2 Department of Radiodiagnosis, Kasturba Medical College, Mangalore, Karnatak, India

Correspondence Address:
Shrijeet Chakraborti
Department of Pathology, Kasturba Medical College, Lighthouse Hill Road, Mangalore - 575 001, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-2870.150498

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Mixed germ cell tumors (GCTs) are aggressive tumors owing to poor response to therapy, frequent recurrence and metastasis. We present here a case of 29-year-old male with recurrent metastatic mixed GCT in the left parietal lobe, with right testicular primary. Interestingly, the recurrent tumor exhibited a seminomatous component, in addition to yolk sac tumor and embryonal carcinoma. The patient was treated with surgery, cranial radiotherapy and cisplatin-based chemotherapy. The metastatic intracranial tumor recurred twice and the patient died 18 months after the first appearance of central nervous system metastasis.


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